A 31-year-old Saskatoon man is among the dead after a crash between a pickup truck and van about 115 kilometres west of Medicine Hat.
Mounties responded to the collision on Highway 36 south of Secondary Highway 875 around 7:15 a.m. Friday.
The 31-year-old was the only person inside the truck, RCMP said in a media release.
The driver of the van, a 26-year-old man from Camrose, Alberta and two passengers a 25-year-old man from Edmonton and 29-year-old Medicine Hat man also died at the scene, according to RCMP.
Six other van passengers were taken to hospital with various injurious.
RCMP continue to investigate the cause of the collision.