A collision Friday evening forced drivers travelling on Highway 11 between Haultain and Dundurn to be detoured for several hours.
RCMP said a transport truck rear-ended another semi after a driver hit a deer.
One of the semis was hauling dangerous goods.
Police closed the north and southbound lanes as a precaution and began to detour traffic on the 663 grid road.
By 4:30 a.m. Saturday the highway re-opened to normal traffic.
Mounties say nothing is believed to have spilled out of the trailer.