The Saskatoon Fire Department was called out to a blaze early Thursday morning.
Crews arrived at 1317 2nd Avenue North shortly after midnight, according to a media release.
They found flames and heavy smoke at the back of the house.
After being told everyone in the home had gotten out, firefghters also evacuated a neighbouring house that was exposed to the flames.
Crews were able to get the blaze under control quickly and no injuries were reported.
Between the home where the fire started and damages to nearby property, the total damage from the fire was estimated at $325,000.