The SPCA is looking for two puppies.

The white husky cross and the fluffy Germane Shepherd cross went missing from the Saskatoon shelter.

According to Marv LeNabat with the SPCA, the pair couldn't have escaped on their own.

"Our main concern obviously is the welfare of the animals because if anyone were to liberate the animals from the shelter, we wonder what kind of care they would give the animals," he said.

"We just want to make sure the animals are safe, that's what we're in the business for and we want to make sure the animals are looked after."

It's difficult to figure out with happened or have a lead because they have numerous visitors to the SPCA shelter daily, said LeNabat.

This isn't the first time, LeNabat has seen animals go missing from the shelter - last time it ended well with someone returning the lost animal.

The SPCA doesn't plan on going to police because they aren't worried about prosecuting, they just want the puppies back, he said.

They have been gone since end of day Wednesday, when the staff doing their regular checks noticed two of the kennels were empty.